The IIS Aragón participates in the conference 'The HRS4R seal in Aragon: strategy, evaluation and future'
October 2, 2024
The Molecular Oncology group project of the IIS Aragón will receive funds from the Monzón Women's Race
October 3, 2024
Researchers from the IIS Aragón have published a study in the journal 'Archivos de Bronconeumología' that suggests that the variation in heart rate during apnea episodes may be a new biomarker of cardiovascular risk
Magazine 'Bronchopulmonology Archives' (Decile 1, Impact Factor: 8.7) published a few weeks ago one of the latest research works by the IIS Aragón Precision Medicine in Respiratory Diseases (PRES) group.
José M. Marín (IP of the group) is the senior author of this research that has been developed in collaboration with groups from USC San Diego and Harvard University in the United StatesOther members of the PRES group also participated as authors in this work, such as David Sanz (Co-PI of the group), Marta Marín, Sergio Alarcón or Eugenio Vicente.
In this study, which is It is included in the group's line of research on sleep apnea, a re-evaluation of the sleep studies carried out on the subjects included in its EPIOSA (Epigenetic modifications and subclinical atherosclerosis in Obstructive Sleep Apnea) patient cohort has been carried out. To do this, an algorithm has been applied that has allowed Automatically obtain how the heart rate varied in each apnea event.
The increase in this value, defined as a variation in the heart rate (delta heart rate), has been associated with an increase in the measurements of the intima media layer of the carotid artery. The growth of this layer means a higher cardiovascular risk, so it has been concluded that this value It could be used as a biomarker of cardiovascular risk in patients with sleep apnea, given its increase in patients who had a greater thickness of the intima media layer in the carotid arteries.
