The Zaragoza startup that detects if your baby does not see well
7 May 2019
Aragonese of the Year reaches its 26th edition tonight
8 May 2019
It shows that "not all people who we thought had Alzheimer's have it" and that "it is very important to understand other elements that contribute to dementia."
The National Institute on Aging (NIH) of the United States presented this Tuesday a guide to distinguish Alzheimer's from Predominantly Limbic Age-Related Dementia (LATE), which has now been defined for the first time and is identified as TDP-43 Encephalopathy.
As published in the scientific journal Brain, the guide, which is aimed at scientists, medical personnel and the general public, specifies the characteristics of LATE as a disease different from Alzheimer's.
Nina Silverberg, director of the Alzheimer's Disease Centers Program at the U.S. National Institutes of Health (NIA), noted that recent "research and clinical evaluations" have shown that "not everyone we thought had Alzheimer's have it" and that "it is very important to understand other (elements) that contribute to dementia.
"The guidance offered in this article, including the definition of LATE, is a crucial step in increasing awareness and advancing research into both this disease and Alzheimer's," said NIH Director Richard Hodes.
The text highlights that "in the past Alzheimer's and dementia were often considered the same thing. There is now a growing appreciation that a variety of diseases and processes that contribute to dementia" are different from Alzheimer's.
TDP-43 is a protein that normally helps regulate gene expression in the brain and other tissues, the guide highlights, noting that "recent research associates problems with the breakdown of this protein with the loss of thinking and memory skills." .
