The inflammatory response protects against invading agents, wounds or tissue damage, including those induced by surgery. These challenges go unnoticed because they resolve naturally and are limited in time without progressing to chronic inflammation.
Chronification of inflammation has a pathophysiological nature and is associated with many of the most prevalent diseases: cardiovascular, neurodegenerative, diabetes, obesity, fatty liver, gastrointestinal inflammation,
cancer, asthma, as well as classic diseases of an inflammatory nature (e.g. arthritis, periodontal, etc.). Today we have selective drugs whose therapeutic action to combat inflammation, chronic pain or tissue damage is based on the inhibition or blocking of pro-inflammatory chemical mediators. As the inflammatory response is protective, its inhibition can cause serious side effects such as immunosuppression.