IpIBA seminar series 2022/2023“Intravenous delivery of BCG into the lung enables antitumor immunity”

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IpIBA seminar series 2022/2023“Intravenous delivery of BCG into the lung enables antitumor immunity”

December 13, 2022 @ 9:30 am - 10:30 am

IpIBA seminar series 2022/2023 “Intravenous delivery of BCG into the lung enables antitumor immunity”

Tuesday, December 13th 2022 From 9:30 to 10:30

Administration of BCG into the bladder was one of the first immunotherapies approved by the FDA and currently is still the treatment of choice for a subset of non-muscle invasive bladder cancer patients. Recently, it was shown that systemic administration of BCG by the intravenous (IV) route is well-tolerated and highly effective at preventing tuberculosis infection in a Rhesus macaque model. Here, we show that systemic administration of BCG by the IV route in a therapeutic scenario slows tumor growth and extends mouse survival in mouse models of B16-F10 lung metastasis and in an orthotopic LLC lung cancer model by enhancing both antitumor innate and adaptive immune responses .

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CIBA, main meeting room, and online via zoom.

Importantly, places are limited: 100 in person and 100 online. If you participate in person, there is no need to register online.

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Details

Date:
13 December, 2022
Time:
9: 30 am - 10: 30 am
Event Categories:
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Organiser

IIS Aragon
See the Organizer's website