EDCTP3: Global Health EDCTP3 Work Program 2025 is published

The Global Health EDCTP3 Work Program 2025 has been published. It is the largest and most ambitious Work Program since the creation of the Joint Undertaking, in 2021. It includes four calls for proposals covering seven topics, with a total budget of €214 million.

The calls will support a range of Research and Innovation Actions (RIA) aimed at developing novel vaccines and therapeutics for tuberculosis, malaria, and neglected tropical diseases:

• Vaccines for reducing the disease burden of tuberculosis in sub-Saharan Africa.
• Malaria therapeutics and clinical development of new antimalarial candidates.
• Accelerating the development of prophylactic vaccines against neglected tropical diseases.

Additionally, Coordination and Support Actions (CSA) will strengthen the enabling environment for conducting clinical research in Africa, through fellowships in public health with an emphasis on biostatistics, epidemiology, and modeling, as well as through regional networks of excellence for preparedness and response to outbreaks:

• Strategic training hubs for fellowships in public health.
• Strengthening the regional networks of excellence and prepared epidemicness consortia.

The rapidly growing climate and health challenge will be addressed in a dedicated topic focused on tackling diarrhoeal diseases. Furthermore, there will be an effort to foster novel and emerging transformative innovations in global health, aiming to serve underserved populations and make interventions more affordable and accessible. Both topics are Research and Innovation Actions (RIA):

• Tackling diarrhoea diseases in the context of climate and health transformative innovations.
• Transformative innovations in global health.

Global Health EDCTP3 will also explore new approaches and ways of collaboration to promote greater efficiency in 2025. A pilot on lump sum contributions in the grant agreements for two call topics is being considered, and more flexible ways of working with contributing partners will be introduced to facilitate increased engagement with Global Health EDCTP3 and forge new and stronger partnerships. 

The calls for proposals will open in late January 2025. Interested consortia are invited to submit a short proposal by March 2025 (first stage). Successful consortia will then be invited to submit a full proposal by September 2025 (second stage).  

Opening Date: Late January 2025.

Deadline (First Stage): March 2025.

Deadline (Second Stage): September 2025.